Graduate Students
Johns Hopkins University:
Danielle Bautista | “Enzyme Generated Aza-Quinone Methides and their Subsequent Alkylation of Biomolecules” | 2022 | Scientist, Nurix |
Anton Kozyryev | “A Search for the Rate Determining Step of Iodotyrosine Deiodinase Catalysis and Minimal Requirement for Enzyme Catalyzed Deiodination” | 2020 | Scientist, Regeneron |
Qi Su | “A Deiodinase Branches Out: Reduction of Nitroaromatics to Facilitate Bioremediation and Debromination in Drosophila to Control Male Fertility” | 2019 | Postdoctoral Researcher, University of California, San Diego |
Zuodong Sun | “Engineering Iodotyrosine Deiodinase Towards Bioremediation of Halophenols and Characterization of a Unique Thermophilic Iodotyrosine Deiodinase from Thermotoga neapolitana” | 2019 | Postdoctoral Researcher, University of California, Los Angeles |
Shane Byrne | “How DNA Packaging and Processing Proteins Affect Dynamic DNA Crosslinking” | 2019 | Postdoctoral Researcher, Massachusetts Institute of Technology |
Nattha Ingavat | “Characterization and Mutation of Iodotyrosine Deiodinase from Haliscomenobacter hydrossis for Detoxification of Iodophenols” | 2017 | Downstream Process Development Senior Supervisor. Abinis, Thailand |
Blessing Deeyaa | “Conjugation of Monofunctional Quinone Methides to DNA Ligands for Promotion of Reversible Alkylation” | 2017 | Scientist, Southwest Research Institute, Utah |
Abhishek Phatarphekar | “The Ubiquity of Iodotyrosine Deiodinase (IYD): Identification of its Signature Sequence and Functional Analysis in a Model Invertebrate” | 2016 | Senior Research Scientist, Reliance Industries Ltd Mumbai |
Mark Hutchinson | “Development of Bifunctional Alkylating Agents for the Association and Migration along DNA” | 2016 | Scientist, AstraZeneca |
Fazel Fakhari | “Enhancing Diffusion of Electrons and Electrophiles in DNA” | 2014 | Endodontist, DDS |
University of Maryland, College Park
Petrina Boucher | “Use Of 2-Deoxyflavin Mononucleotide To Probe Substrate-Flavin Interactions Within Iodotyrosine Deiodinase” | 2015 | Coordinator at ICNA Relief |
Shalini Saha | “Dihydropyrrole Formation During Sibiromycin Biosynthesis” | 2015 | Associate Medical Director, Medical Strategy and Scientific Affairs at BGB |
Jimin Hu | “The Interplay of Substrate, Protein and Its Cofactor in Controlling the Catalytic Properties of Human Iodotyrosine Deiodinase” | 2014 | Scientist, College of Chemistry, Nankai University |
Michael McCrane | “Trapping Labile Adducts Formed Between an Ortho-Quinone Methide and DNA” | 2012 | Technical Advisor, Paul Hastings LLP |
Chengyun Huang | “Design and Synthesis of an Electron Rich Quinone Methide Precursor and Sequence Directed Alkylation of DNA” | 2012 | Scientist, Geological Engineering Investigation Institute of Sichuan |
Jennifer Buss | “Iodotyrosine Deiodinase from Selected Phyla Engineered for Bacterial Expression” | 2012 | CEO, Potomac Institute for Policy Studies |
Yang Liu | “Target Alkylation of Single and Double Strand DNA by Peptide Nucleic Acids” | 2011 | National Institute for Food and Drug Control, Beijing |
Huan Wan | “Reversible Quinone Methide Alkylation of DNA” | 2009 | Professor, School of Chemistry and Chemical Engineering, Nanjing University |
Patrick M. McTamney | “Catalytic Features of the Iodine Salvaging Enzyme Iodotyrosine Deiodinase” | 2009 | CEO, new start up company |
Neil P. Campbell | “Investigation into the Driving Force Dependence of Excess Electron Transport in Duplex DNA” | 2009 | Associate Director, CryoLife |
Amethist S. Finch | “Fundamentals of Excess Electron Transport in Biologically Relevant Systems” | 2008 | Associate For Strategy Development, DEVCOM Army Research Laboratory |
Emily E. Weinert | “Understanding Quinone Methide Reactivity: Kinetics, Trapping and Substituent Effects” | 2006 | Associate Professor of Biochemistry & Molecular Biology, Penn State University |
James A. Watson, Jr. | “Insight into the Structure and Mechanism of Iodotyrosine Deiodinase, the First Mammalian Member of the NADH Oxidase/Flavin Reductase Superfamily” | 2006 | Infrastructure Management Specialist at Chemical and Biological Defense ODASD |
Willem Veldhuyzen | “Specificity of DNA Alkylation by Simple and Conjugated Quinone Methide Intermediates” | 2002 | |
Jessica Friedman | “Iodotyrosine Deiodinase: Purification and Characterization” | 2001 | Associate Director, Biophysics & Assay Development at Arrakis Therapeutics |
Matthew Holman | “Determinants of UV-Induced Cyclobutane Pyrimidine Dimer Hot Spots in DNA” | 2000 | Director, Office of Science at the Center for Tobacco Products, FDA |
Manvinder Wahi | “Synthesis of Quinone Methide Precursors as Alkylating Agent” | 1999, M.S. | |
Praveen Pande | “Inducible DNA Alkylation and Cross-Linking via Quinone Methide Intermediates” | 1998 | Director of Chemistry, Enzo Biochemistry |
Madhushree Ghosh | “Carcinogenic Metal-Mediated Oxidation of Proteins and DNA” | 1998 | Vice President, Global Strategic Alliances and Projects, Pharma Services at NeoGenomics Laboratories |
University of Stony Brook
Ning Tang | “Probing DNA Conformation with Metal Complexes” | 1996 | Director, Global Strategic Account Management at Waters Corporation |
Hui-Chen Shi | “Binding Studies of DNA with Nickel Complexes” | 1996 | Patent Attorney |
Ping Zheng | “Conformational Studies of Nucleic Acids with Metal Complexes” | 1996 | Senior Manager, Roche Molecular Systems |
Qingping Zeng | “Development of Inducible DNA Crosslinking Agents” | 1995 | Chairman Board of Directors, ZPG Pharma Inc |
Gurpreet Gill | “Protein and Nucleic Acid Modification by Nickel” | 1993 | Office of Lifecycle Drug Products, FDA |
Hyunmin Kang | “Photo-Induced Site Specific DNA Modification by Antisense Conjugates of Xanthone and 1,4-Dimethylanthraquinone” | 1993 | |
Ute Hänsler | “Intrinsic Reactivity of DNA Secondary Structure” | 1993 | Consultant, Business Constellations |
Tianhu Li | “Sequence Selective Modification of DNA with a Silyl Phenol Ether-Oligodeoxynucleotide Conjugate” | 1992 | Associate Professor, Nanyang Technological University |
Xiaoyan Ma | “Characterization of Peroxidases by ortho-Substituted Phenols” | 1991 | Alza Corporation |
Moneesh Chatterjee | “Site Specific Modification of Nucleic Acids” | 1991 | Bristol-Myers Squibb, retired |
Elisa Woolridge | “Development of Indole Analogues for the Study of Tryptophanase and Tryptophan Synthase” | 1990 | Associate Professor, Marist College |
Postdoctoral Associates
Jonathan Musila | 2017-2018 | Former Postdoctoral Researcher, University of Pennsylvania (Rhoades Lab), in transition to an academic position |
Arnab Mukherjee | 2012-2014 | Scientist, Sensei Bio, Rockville MD |
Watchalee Chuenchor | 2011 | Scientist at NIH, NIAID |
Kostyantyn Bobyk | 2010-2012 | Senior Manager, Otsuka Pharmaceutical Companies, NJ |
Ying Lin | 2006-2008 | Review Chemist, FDA, College Park, MD |
Cliff Rossiter | 2005-2007 | Associate Prof., Dept. of Chemistry, SUNY Potsdam, NY |
Mazen Hanbali | 2005-2006 | Teacher, FormaScience, Strasbourg, France |
Dalip Kumar | 2002-2004 | Professor, Dept. of Chemistry, Birla Institute of Technology and Science Pilani, India |
Emilia Modica, | 2002-2003 | Sojitz Corporation, Milan, Italy |
Takeo Ito | 2000-2003 | Deputy Director of the University Collaboration, Minister of Economy, Trade & Industry, Toyko, Japan |
Qibing Zhou | 1999-2002 | Prof., Huazhong University of Science and Technology, Wuhan, PROC |
Meinrado Samala | 1999-2003 | |
Xiang Zhou | 1998-2001 | Prof. and Dean, College of Chemistry and Molecular Science, Wuhan University, PROC |
Anne Johnson | 1998-2000 | Assoc. Prof., Ryerson Polytechnic University, Toronto, Canada |
Munetaka Kunishima | 1994-1996 | Prof. Dept. of Pharmacy, Kanazawa University, Japan |
Visiting Scholars
Tuomas Lönnberg | 2013-2014 | Fulbright Fellow, University of Turku, Finland |
Seung Jae Lee | 2009 | University of MD, Baltimore |
Ravinder Kodela | 2007-2008 | City College of New York |
Alessandro Livieri | 2007-2008 | University of Pavia |
Juan Carlos Solis Sainz | 2004-2005 | Universidad Autonoma de Queretaro |
Lei Li | 2003-2004 | Johns Hopkins University |
Sunita Thyagarajan | 2002-2004 | Johns Hopkins University |
Kristi Humphreys | 2000-2001 | Johns Hopkins University |
Xiaoying Chen | 1990-1992 | University of Stony Brook |
Christian Kuber | 1988-1989 | University of Tübingen |
Maria Benincasa | 1987 |
Undergraduate Research Associates
Johns Hopkins University
Keelin Reilly | 2019-2021 | Corteva Agriscience |
Idris Barakat (Amgen Scholar) | Summer 2019 | Postbaccalaureate CRTA Research Fellow at National Cancer Institute |
Gregory Berumen (Leadership Alliance) | Summer 2018 | PhD program in Chemical and Biomolecular Engineering at Vanderbilt University |
Azam Hussein (Summer Greer Undergraduate Research Award) | 2017-2019 | Ph.D. program, Univ. of Michigan |
Forrest Hammel (Summer Greer Undergraduate Research Award) | 2017-2019 | Chemical Biology Ph.D program, Harvard |
Carla Quiñones (Bio-REU, Leadership Alliance) | Summer 2017 | Doctor of Pharmacy Candidate at University of Maryland-Baltimore |
Isabelle Engelberg | 2015-2017 | Chemistry Biology Interface graduate student, UNC |
Sierra Williams (Bio-REU) | Summer 2014 | Ph.D., Chemical Biology, UC Irvine, starting as an Asst. Prof. in the Department of Chemistry, Claremont Colleges |
Obinna Wogu (Leadership Alliance) | Summer 2014 | MD from Thomas Jefferson University School of Medicine |
University of Maryland, College Park
Omer Ad, Howard Hughes Fellow | “Trapping Quinone Methide-2’-Deoxyadenosine Adducts” | 2010-2012 | Scientist at Quantum-Si, CT |
Yun-Yun (Kathy) Chen, Howard Hughes Fellow | “Anthracenes as donors for Excess Electron Transfer” | 2008-2010 | M.D., Anesthesiology |
Yishan Zhou, Howard Hughes Fellow | “Iodotyrosine Deiodinase: Mutagenesis and Expression of Human IYD in E. coli and Identifying the Physiological Reductase” | 2007-2009 | Jane Coffin Childs Post-doctoral Fellow, Univ. of Berkeley, CA |
Angel Li, Howard Hughes Fellow | “Synthesis of DNA-Aminoanthracene Conjugates for Characterization of Excess Electron Transfer” | 2007-2008 | M.D. |
Jennifer Gehret | “Expression and in vitro Refolding Studies of the Thioredoxin Fusion to Iodotyrosine Deiodinase” | 2005-2007 | Ph.D. U. of Michigan |
Timothy J. Simons, Howard Hughes Fellow | “Optimizing the Efficiency of Excess Electron Transfer in DNA: Studies on 1-aminoanthracene and 2-aminoanthracene” | 2005-2007 | M.D., Pediatrician |
Musaddiq Awan, Rollinson Fellow | 2005 | ||
Chuck Mitchell Howard Hughes Fellow | “Reactivity of a Model Quinone Methide: Substituent Effects and Trapping” | 2004-2006 | Medical Doctor |
Oz Scott Halpern | 2003 | Medical Doctor | |
Ling Chen, Howard Hughes Fellow | 2003-2005 | Medical Doctor | |
Theresa Jackson, Howard Hughes Fellow | 2001 | ||
Kristen Frankenfield, Howard Hughes Fellow | 2001-2002 | Pharm. D., UCSF | |
David Lam, Howard Hughes Fellow | 2000-2003 | Medical Doctor | |
Eun Sun (Grace) Han, Howard Hughes Fellow | 1998-2000 | Medical Doctor | |
Helina Kassahun, Howard Hughes Fellow | 1997-1998 | Medical Doctor | |
Jason Shearer | “Development of a New Synthetic Method for Nickel Salen Derivatives and Analysis of Products Formed by Alkylation of DNA by a Quinone Methide Intermediate” | 1997-1998 | Semmes Distinguished Professor of Chemistry, Trinity College, Texas |
Jeannie Lee, Howard Hughes Fellow | 1995-1997 |
University of Stony Brook
Ilya Voloshin | 1993 | ||
Felicia Malkiel | “The Formation of Thymine Dimers and the Role of DNA Structure” | 1992-1993 | |
Carl Goodchild | 1992-1993 | M.D., family medicine | |
William Greenberg | “Quinone Methide Alkylation of DNA” | 1990-1992 | NIH, Scientific Review Office |
Stacey Shlachtman | 1991 | ||
Mark Rivellese | “The Synthesis of ortho-Alkylated Tyrosine Derivatives” | 1989-1990 | M.D., Ophthalmology |
Jorge Kizer | 1989 | M.D., Cardiology | |
Stephanie Dobbins | 1989 | D.V.M., Veterinarian | |
William Wichrowski | 1998 | ||
Mark Ackerman | “Oxidative Reactivities of Sequence Specific Oligonucleotides” | 1987-1988 | |
Michael Sypes | “Site Specific Photo-Induced Modification of DNA” | 1987-1988 | |
Minisha Thakore | 1986-1987 | ||
Stacey Prusiewicz | “Oxidation Degradation of d(CG)6” | 1987 | |
Michael Allehverdi | 1986 | ||
Barbara Schagawat | 1986 |