223. Identifying Poly(ADP-ribose)-Binding Proteins With Photoaffinity-Based Proteomics. Dasovich, M.; Beckett, M. Q.; Bailey, S.; Ong, S.; Greenberg, M. M.; Leung, A. K. L. J. Am. Chem. Soc. 2021, 143, 3037-3042.
224. Selective Inhibition of DNA Polymerase b by a Covalent Inhibitor. Yuhas, S. C.; Laverty, D. J.; Lee, H.; Greenberg, M. M. J. Am. Chem. Soc. 2021, 143, 8099-8107.
225. Sequence Context Effects of Replication of Fapy•dG in Three Mutational Hot Spot Sequences of the p53 Gene in Human Cells. Bacurio, J. H.; Yang, H.; Naldiga, S.; Powell, B. V.; Ryan, B. J.; Freudenthal, B. D.; Greenberg, M. M. Basu, A. K. DNA Repair 2021, 108, 103213.
226. Protein Domain Specific Covalent Inhibition of Human DNA Polymerase b. Yuhas, S. C.; Majumdar, A.; Greenberg, M. M. ChemBioChem 2021, 22, 2619-2623. Designated by the editor as a Very Important Paper.
227. Suppression of DNA Polymerase b Activity is Synthetically Lethal in BRCA1-Deficient Cells. Yuhas, S. C.; Mishra, A.; DeWeese, T. L.; Greenberg, M. M. ACS Chem. Biol. ACS Chem. Biol. 2021, 16, 1339-1343.
228. Reactivity and DNA Damage by Independently Generated 2′-Deoxycytidin-N4-yl Radical. Peng, H.; Jialong, J.; Mortimer, I. P.; Zehan, M.; Su, H.; Greenberg, M. M. J. Am. Chem. Soc. 2021, 143, 14738-14747.
229. Intracellular Formation of A DNA Damage-Induced, Histone Post-translational Modification Following Bleomycin Treatment. Jacinto, M. P.; Fried, S. D.; Greenberg, M. M. Jacinto, M. P.; Fried, S. D.; Greenberg, M. M. J. Am. Chem. Soc. 2022, 144, 7600-7605.
230. Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and During DNA Replication. Ryan, B. J.; Yang, H.; Bacurio, J.H.; Smith, M. R.; Basu, A. K.; Greenberg,M. M.; Freudenthal, B. D. J. Am. Chem. Soc. 2022, 144, 8054-8065.
231. Local Alteration of Ionic Strength in a Nucleosome Core Particle and its Effect on N7-Methyl-2’-deoxyguanosine Depurination. Wen, T.; Yang, K.; Greenberg, M. M. Biochemistry 2022, 61, 2221-2228.
232. Covalent Modification of Bromodomain Proteins by Peptides Containing a DNA Damage-Induced, Histone Post-Translational Modification. Jacinto, M. P.; Heidenreich, D.; Müller, S.; Greenberg, M. M. ChemBioChem 2022, 23, e202200373.
233. Histone Deacetylase 1 Inhibition by Peptides Containing a DNA Damage-Induced, Non-enzymatic, Histone Covalent Modification. Jacinto, M. P.; Greenberg, M. M. Biochemistry 2023, 62, 1388-1393.
234. 8-Oxo-2’-deoxyguanosine Replication in Mutational Hot Spot Sequences of the p53 Gene in Human Cells is Less Mutagenic Than That of the Corresponding Formamidopyrimidine. Stanio, S.; Bacurio, J. H.; Yang, H.; Greenberg, M. M.; Basu, A. K. Chem. Res. Toxicol. 2023, 36, 782-789.
235. Photochemical and Single Electron Transfer Generation of 2¢-Deoxycytidin-N4-yl Radical From Oxime Esters. Peng, H.; Vu, S.; Retes, P.; Ward, S.; Kumar, A.; Sevilla, M. D.; Adhikary, A.; Greenberg, M. M. J. Org. Chem. 2023, 88, 7381-7390.
237. Synergistic Effects on the Mutagenicity of Tandem Lesions Containing 8-Oxo-7,8-dihydro-2ʹ-deoxyguanosine or Fapy•dG Flanked by a 3ʹ 5-Formyl-2ʹ-deoxyuridine in Human Cells. Bacurio, J. H.; Gao, S.; Yang, H.; Basu, A. K.; Greenberg, M. M. DNA Repair 2023, 129, 103527.
238. DNA-Histone Cross-link Formation via Hole Trapping in Nucleosome Core Particles. Wen, T.; Kermarrec, M.; Dumont, E.; Gillet, N.; Greenberg, M. M. J. Am. Chem. Soc. 2023, 145, 23702-23714.
239. Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy•dG. Gao, S.; Hou, P.; Oh, J.; Wang, D.; Greenberg, M. M. J. Am. Chem. Soc. 2024, 146, 6274-6282.
240. Biochemical and Structural Characterization of Fapy•dG Replication by Human DNA Polymerase b. Gao, S.; Oden, P. N.; Ryan, B. J.; Yang, H.; Freudenthal, B. D.; Greenberg, M. M. Nucleic Acids Res 2024, 52, 5392-5405.
241. DNA-Protein Cross-Links With N7-Methyl-2’-deoxyguanosine And Their Contribution To Cytotoxicity. Wen, T.; Zhao, S.; Stingele, J.; Ravanat, J.; Greenberg, M. M. Chem. Res. Toxicol. 2024, 37, 814-823.
242. Promoter Dependent RNA Polymerase II Bypass of the Epimerizable DNA Lesion, Fapy•dG and 8-Oxo-2′-deoxyguanosine. Gao, S.; Tahara, Y.; Kool, E. T.; Greenberg, M. M. Nucleic Acids Res. 2024, 52, 7437-7446.
243. T7 RNA Polymerase Catalyzed Transcription of the Epimerizable DNA Lesion, Fapy•dG and 8-Oxo-2′-deoxyguanosine. Gao, S.; Hou, P.; Wang, D.; Greenberg, M. M. J. Biol. Chem. 2024, 300, 107719.
244. 8-OxodGuo and Fapy•dG Mutagenicity in Escherichia coli Increases Significantly When They are Part of a Tandem Lesion With 5-Formyl-2ʹ-deoxyuridine. Dasgupta, S.; Gao, S.; Yang, H.; Greenberg, M. M.; Basu, A. K. Chem. Res. Toxicol. 2024, 37, 1445-1452.
245. A Human High-Fidelity DNA Polymerase Holoenzyme Has a Wide Range of Lesion Bypass Activities. Dannenberg, R. L.; Cardina, J. A.; Washington, H.; Gao, S.; Greenberg, M. M.; Hedglin, M. Nucleic Acids Res.2025, 53, gkaf646.
246. Inhibitors of SAMHD1 Obtained From Chemical Tethering to the Guanine Antiviral Acyclovir. Egleston, M.; Bhat, S.; Howlader, A. H.; Bianchet, M. A.; Liu, Y.; Lopez Rovira, L. M.; Smith, B.; Greenberg, M. M.; Stivers, J. T. Biochemistry 2025, 64, 1109-1120.
247. Uridine Embedded Within DNA is Repaired by Uracil DNA Glycosylase via a Mechanism Distinct From That of RNase H2. Fan, C.; Zhan, X.; Guo, F.; Li, Q.; Lu, K.; Shan, X.; Zhou, Y.; Ren, M.; Greenberg, M. M.; Liu Y.; Zhou, C. J. Am. Chem. Soc. 2025, 147, 11574-11583.
248. A Chimeric Bis-Electrophile for Selective DNA-Protein Cross-Linking Reveals an Unknown Source of Nitrogen Mustard Cytotoxicity. Jiang, X.; Vu, S.; Yu, H.; Greenberg, M. M. J. Am. Chem. Soc. 2025, 147, 31839-31848.
249. Inhibition of DNA Polymerase β by a Noncompetitive Inhibitor. Howlader, A. H.; Jiang, X.; Zhou, Z.; Greenberg, M. M. J. Org. Chem. 2025, 90, 12849-12859. (PMC: 12431629) Selected as a Featured Article in the Journal by the Editors. Featured as an ACS Editors\’ Choice. The ACS Editors\’ Choice initiative highlights one article each day that is chosen from the entire ACS portfolio.