The Greenberg Group > 2006-2010

2006-2010

  1. Oxygen Independent DNA Interstrand Cross-Link Formation by a Nucleotide Radical. Hong, I. S.; Ding, H.; Greenberg, M. M. J. Am. Chem. Soc. 2006, 128, 485-491.
  2. Replication of an Oxidized Abasic Site in Escherichia coli by a dNTP-Stabilized Misalignment Mechanism that Reads Upstream and Downstream Nucleotides. Kroeger, K. M.; Kim, J.; Goodman, M. F.; Greenberg, M. M. Biochemistry 2006, 45, 5048-5056.
  3. Genetic Effects of Oxidative DNA Damages: Comparative Mutagenesis of the Imidazole Ring-Opened Formamidopyrimidines (Fapy lesions) and 8-Oxopurines in Simian Kidney Cells. Kalam, M. A.; Haraguchi, K.; Chandani, S.; Loechler, E. L.; Moriya, M.; Greenberg, M. M.; Basu, A. K. Nucleic Acids Res. 2006, 34, 2305-2315.
  4. Radiosensitization by a Modified Nucleotide that Produces DNA Interstrand Cross-links Under Hypoxic Conditions. Hong, I. S.; Ding, H.; Greenberg, M. M. J. Am. Chem. Soc. 2006, 128, 2230-2231.
  5. Reactivity of the C2′-Oxidized Abasic Lesion and Its Relevance to Interactions With Type I Base Excision Repair Enzymes. Greenberg, M. M.; Kreller, C. R.; Young, S. E.; Kim, J. Chem. Res. Toxicol. 2006, 19, 463-468.
  6. Synthesis, DNA Polymerase Incorporation, and Enzymatic Phosphate Hydrolysis of Formamidopyrimidine Nucleoside Triphosphates. Imoto, S.; Patro, J. N.; Jiang, Y. L.; Oka, N.; Greenberg, M. M. J. Am. Chem. Soc. 2006, 128, 14606-14611.
  7. Use of Fluorescent Sensors to Determine that 2-Deoxyribonolactone is the Major Alkali-Labile Deoxyribose Lesion Produced in Oxidatively Damaged DNA. Xue, L.; Greenberg, M. M. Angew. Chem. Int. Ed. 2007, 46, 561-564.
  8. Hole Migration is the Major Pathway Involved in Alkali-Labile Lesion Formation in DNA by the Direct Effect of Ionizing Radiation. Ding, H.; Greenberg, M. M. J. Am. Chem. Soc. 2007, 129, 772-773.
  9. Characterization and Mechanism of Formation of Tandem Lesions in DNA by a Nucleobase Peroxyl Radical. Hong, I. S.; Carter, K. N.; Sato, K.; Greenberg, M. M. J. Am. Chem. Soc. 2007, 129, 4089-4098.
  10. Facile Quantification of Lesions Derived from 2′-Deoxyguanosine in DNA. Xue, L.; Greenberg, M. M. J. Am. Chem. Soc. 2007, 129, 7010-7011.
  11. Studies on the Replication of the Ring Opened Formamidopyrimidine, Fapy•dG in E. coli. Patro, J. N.; Wiederholt, C. J.; Jiang, Y. L.; Delaney, J. C.; Essigmann, J. M.; Greenberg, M. M. Biochemistry 2007, 46, 10202-10212.
  12. Selective Detection and Quantification of Oxidized Abasic Lesions in DNA. Dhar, S.; Kodama, T.; Greenberg, M. M. J. Am. Chem. Soc. 2007, 129, 8702-8703.
  13. The Human Werner Syndrome Protein Stimulates Repair of Oxidative DNA Base Damage by the DNA Glycosylase Neil1. Das, A.; Boldogh, I.; Lee, J. W.; Harrigan, J. A.; Hegde, M. L.; Piotrowski, J.; de Souza-Pinto, N.; Ramos, W.; Greenberg, M. M.; Hazra, T. K.; Mitra, S.; Bohr, V. A. J. Biol. Chem. 2007, 282, 26591-26602.
  14. DNA Strand Damage Product Analysis Provides Evidence That the Tumor Cell-Specific Cytotoxin Tirapazamine Produces Hydroxyl Radical and Acts as a Surrogate for O2. Chowdhury, G.; Junnotula, V.; Daniels, J. S.; Greenberg, M. M.; Gates, K. S. J. Am. Chem. Soc. 2007, 129, 12870-12877.
  15. -Radiolysis Produces Interstrand Cross-links in DNA Involving Thymidine. Ding, H.; Greenberg, M. M. Chem. Res. Toxicol. 2007, 20, 1623-1628.
  16. Recognition and Repair of Formamidopyrimidines by 8-Oxoguanine Glycosylases. Krishnamurthy,, N.; Haraguchi, K.; Greenberg, M. M.; David, S. S. Biochemistry 2008, 47, 1043-1050.
  17. DNA Tandem Lesion Repair by Strand Displacement Synthesis and Nucleotide Excision Repair. Imoto, S.; Bransfield, L. A.; Croteau, D. L.; Van Houten, B.; Greenberg, M. M. Biochemistry 2008, 47, 4306-4316.
  18. Facile SNP Detection Using Bifunctional, Cross-Linking Oligonucleotide Probes. Peng, X.; Greenberg, M. M. Nucleic Acids Res. 2008, 36: e31.
  19. DNA Polymerase Bypass in vitro and in E. coli of a C-Nucleotide Analogue of Fapy•dG. Wiederholt, C. J.; Weledji, Y. N.; Delaney, M. O.; Greenberg, M. M. Bioorganic & Med. Chem. 2008, 16, 4029-4034.
  20. Synthesis and Analysis of Oligonucleotides Containing Abasic Site Analogues. Huang, H.; Greenberg, M. M. J. Org. Chem. 2008, 73, 2695-2703.
  21. Hydrogen Bonding Contributes to the Selectivity of Nucleotide Incorporation Opposite an Oxidized Abasic Lesion by DNA Polymerase. Huang, H.; Greenberg, M. M. J. Am. Chem. Soc. 2008, 130, 6080-6081.
  22. Self-Promoted DNA Interstrand Cross-link Formation by an Abasic Site. Sczepanski, J. T.; Jacobs, A. C.; Greenberg, M. M. J. Am. Chem. Soc. 2008, 130, 9646-9647.
  23. Interstrand Cross-link Formation in Duplex and Triplex DNA by Modified Pyrimidines. Peng, X.; Hong, I. S.; Li, H.; Seidman, M. M.; Greenberg, M. M. J. Am. Chem. Soc. 2008, 130, 10299-10306.
  24. Mechanism of Replication Termination as Revealed by Tus-mediated Polar Arrest of a Sliding Helicase. Bastia, D.; Zzaman, S.; Krings, G.; Saxena, M.; Peng, X.; Greenberg, M. M. Proc. Natl. Acad. Sci. USA 2008, 105, 12831-12836.
  25. Protein Binding has a Large Effect on Radical Mediated DNA Damage. Peng, X.; Pigli, Y.; Rice, P. A.; Greenberg, M. M. J. Am. Chem. Soc. 2008, 130, 12890-12891.
  26. Multinuclear NMR and Kinetic Analysis of DNA Interstrand Cross-link Formation. Ding, H.; Majumdar, A.; Tolman, J. R.; Greenberg, M. M. J. Am. Chem. Soc. 2008, 130, 17981-17987.
  27. Competitive Inhibition of Uracil DNA Glycosylase by a Modified Nucleotide Whose Triphosphate is a Substrate for DNA Polymerase. Huang, H.; Stivers, J. T.; Greenberg, M. M. J. Am. Chem. Soc. 2009, 131, 1344-1345.
  28. Scope and Mechanism of Interstrand Cross-link Formation by the C4′-Oxidized Abasic Site. Sczepanski, J. T.; Jacobs, A. C.; Majumdar, A.; Greenberg, M. M. J. Am. Chem. Soc. 2009, 131, 11132-11139.
  29. Photochemical Generation and Reactivity of the 5,6-Dihydrouridin-6-yl Radical. Newman, C. A.; Resendiz, M.; Sczepanski, J. T.; Greenberg, M. M. J. Org. Chem. 2009, 74, 7007-7012.
  30. Double-Strand Break Formation During Nucleotide Excision Repair of a DNA Interstrand Cross-link. Sczepanski, J. T.; Jacobs, A. C.; Van Houten, B.; Greenberg, M. M. Biochemistry 2009, 48, 7565-7567.
  31. The Mutagenicity of Thymidine Glycol in Escherichia Coli is Increased When it is Part of a Tandem Lesion. Huang, H.; Imoto, S.; Greenberg, M. M. Biochemistry 2009, 48, 7833-7841.
  32. DNA Interstrand Cross-link Formation by the 1,4-Dioxobutane Abasic Lesion. Guan, L.; Greenberg, M. M. J. Am. Chem. Soc. 2009, 131, 15225-15231.
  33. Single and Double Strand Incisions During Nucleotide Excision Repair of a DNA Interstrand Cross-link. Peng, X.; Ghosh, A. K.; Van Houten, B.; Greenberg, M. M. Biochemistry 2010, 49, 11-19.