Please let us know when you publish papers that utilized our instrumentation.

2024

Barrick Lab

Unraveling paralog-specific Notch signaling through thermodynamics of ternary complex formation and transcriptional activation of chimeric receptors

2023

Lecomte Lab	Architectural digest: Thermodynamic stability and domain structure of a consensus monomeric globin
Kavran lab	Dimerization and autophosphorylation of the MST family of kinases are controlled by the same set of residues
Barrick Lab	Cooperativity of a seven-repeat array from topoisomerase V
Fleming Lab	FkpA enhances membrane protein folding using an extensive interaction surface

Lecomte Lab	Architectural digest: Thermodynamic stability and domain structure of a consensus monomeric globin
Kavran lab	Dimerization and autophosphorylation of the MST family of kinases are controlled by the same set of residues
Barrick Lab	Cooperativity of a seven-repeat array from topoisomerase V
Fleming Lab	FkpA enhances membrane protein folding using an extensive interaction surface

2022

Bowman Lab	Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state
Frueh Lab	Global protein dynamics as communication sensors in peptide synthetase domains
Mao Lab	α-Synuclein fibril-specific nanobody reduces prion-like α-synuclein spreading in mice
Huang Lab	Directed evolution of nonheme iron enzymes to access abiological radical-relay C(sp3)-H azidation
Kokkoli Lab	A localized enantioselective catalytic site on short DNA sequences and their amphiphiles
Kokkoli Lab	Supramolecular assembly of Single-uail ssDNA-amphiphiles through π-π Interactions

2021

Barrick Lab	Surface residues and nonadditive interactions stabilize a consensus homeodomain protein
Barman Lab	Molecular radiative energy shifts under strong oscillating fields
Barman Lab	Role of Aqueous-Phase Calcination in Synthesis of Ultra-Stable Dye-Embedded Fluorescent Nanoparticles for Cellular Probing
Fried Lab	Nonrefoldability is pervasive across the E. coli proteome
Greenberg Lab	Protein domain specific covalent inhibition of human DNA polymerase ß
Greenberg Lab	Selective inhibition of DNA polymerase ß by a covalent inhibitor
Hilser Lab	Tumor susceptibility gene 101 regulates the glucocorticoid receptor through disorder-mediated allostery
Hilser Lab	Conserved allosteric ensembles in disordered proteins using TROSY/anti-TROSY R2-filtered spectroscopy

2020

Fleming Lab	SurA is a cryptically grooved chaperone that expands unfolded outer membrane proteins
Cui Lab	Selective capture and recovery of monoclonal antibodies by self-assembling supramolecular polymers of high affinity for protein binding
Culotta Lab	Copper-Only Superoxide Dismutase Enzymes and Iron Starvation Stress in Candida Fungal Pathogens
Fleming Lab	Domain interactions determine the conformational ensemble of the periplasmic chaperone SurA
Kavran Lab	Biophysical characterization fo SARAH domain-mediated multimerization of Hippo pathway complexes in Drosophila
Tovar Lab	Computationally guided tuning of amino acid configuration influences the chiroptical properties of supramolecular peptide-pi-peptide nanostructures

2019

Barrick Lab	A second backbone: The contribution of a buried asparagine ladder to the global and local stability of a leucine-rich repeat protein
Tovar Lab	Controlling supramolecular chirality in peptide-pi-peptide networks by variation of the alkyl spacer length
Meyers Lab	X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1-deoxy-D-xylulose 5-phosphate synthase reaction coordinate
Barrick Lab	Consensus sequence design as a general strategy to create hyperstable, biologically active proteins
Ha Lab	Extreme mechanical diversity of human telomeric DNA revealed by fluorescence-force spectroscopy
Barrick and Ha Labs	Functional instability allows access to DNA in longer transcription Activator-Like effector (TALE) arrays
Barrick Lab	Extreme stability in de novo-designed repeats arrays is determined by unusually stable short-range interactions
Tovar Lab	Torsional impacts on quaterthiophene segments confined within peptidic nanostructures

2018

Garcia-Moreno Lab	Dielectric properties of a protein probed by reversal of a buried ion pair
Greenberg Lab	Expanded substrate scope of DNA polymerase theta and DNA polymerase beta: Lyase activity on the 5′-overhangs and clustered lesions
Elisseeff Lab	Cyclodextrin Modulated Type I Collagen Self-Assembly to Engineer Biomimetic Cornea Implants
Greenberg Lab	Mechanistic insight through irreversible inhibition:DNA polymerase theta uses a common active site for polymerase and lyase activities
Hilser Lab	Assessing allostery in intrinsically disordered protein with ensemble allosteric model
Hilser Lab	Dynamic allostery can drive cold adaptation in enzymes
Lecomte Lab	Lysine as a heme iron ligand: A property common to three truncated hemoglobins from Chlamydomonas reinhardtii
Lecomte Lab	Replacement of the distal histidine reveals a noncanonical heme binding site in a 2-on-2 hemoglobin
Meyers Lab	Oxidative decarboxylation of pyruvate by 1-deoxy-D-xyulose 5-phosphate synthase, a central metabolic enzyme in bacteria

2017

Barrick Lab	Control of transcriptional activity by design of charge patterning in the intrinsically disordered RAM region of the Notch receptor
Barrick Lab	Creating a homeodomain with high stability and DNA binding affinity by sequence averaging
Frueh Lab	Molecular cross-talk between nonribosomal peptide synthetase carrier proteins and unstructured linker regions
Hilser Lab	Structural stability of the coiled-coil domain of tumor susceptibility
Tovar Lab	Nonresonant and local field effects in peptidic nanostructures bearing oligo (p-phenylenevinylene) units
Tovar Lab	Kinetically controlled coassembly of multichromophoric peptide hydrogelators and the impacts on energy transport

2016

Barrick Lab	Broken TALEs: transcription activator-like effectors populate partly folded states
Tovar Lab	Cross-linking approaches to tuning the mechanical properties of peptide π‑electrom hyrdogels

2015

Barrick Lab	Effects of linker length and transient secondary structure elements in the intrinsically disordered Notch RAM region on Notch signaling
Barrick Lab	A naturally occurring repeat protein with high internal sequence identity defines a new class of TPR-like proteins
Bortvan Lab	A unique HMG-Box domain of mouse maelstrom binds structured RNA but not double stranded DNA
Tovar Lab	Sequence-dependent mechanical, photophysical and electrical properties of pi-conjugated peptide hydrogelators
Ostermeier Lab	Design of protein switches based on an ensemble model of allostery

2014

Lecomte Lab	Characterization of THB1, a Chlamydomonas reinhardtii truncated hemoglobin: linkage to nitrogen metabolism and identification of lysine as the distal heme ligand
Stivers Lab	GTP activator and dNTP substrates of HIV-1 restriction factor and SAMHD1 generate a long-lived activated state