Please let us know when you publish papers that utilized our instrumentation.


Lecomte LabArchitectural digest: Thermodynamic stability and domain structure of a consensus monomeric globin
Kavran labDimerization and autophosphorylation of the MST family of kinases are controlled by the same set of residues
Barrick LabCooperativity of a seven-repeat array from topoisomerase V
Fleming LabFkpA enhances membrane protein folding using an extensive interaction surface


Bowman LabNucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state
Frueh LabGlobal protein dynamics as communication sensors in peptide synthetase domains
Mao Labα-Synuclein fibril-specific nanobody reduces prion-like α-synuclein spreading in mice
Huang LabDirected evolution of nonheme iron enzymes to access abiological radical-relay C(sp3)-H azidation
Kokkoli LabA localized enantioselective catalytic site on short DNA sequences and their amphiphiles
Kokkoli LabSupramolecular assembly of Single-uail ssDNA-amphiphiles through π-π Interactions


Barrick LabSurface residues and nonadditive interactions stabilize a consensus homeodomain protein
Barman LabMolecular radiative energy shifts under strong oscillating fields
Barman LabRole of Aqueous-Phase Calcination in Synthesis of Ultra-Stable Dye-Embedded Fluorescent Nanoparticles for Cellular Probing
Fried LabNonrefoldability is pervasive across the E. coli proteome
Greenberg LabProtein domain specific covalent inhibition of human DNA polymerase ß
Greenberg LabSelective inhibition of DNA polymerase ß by a covalent inhibitor
Hilser LabTumor susceptibility gene 101 regulates the glucocorticoid receptor through disorder-mediated allostery
Hilser LabConserved allosteric ensembles in disordered proteins using TROSY/anti-TROSY R2-filtered spectroscopy


Fleming LabSurA is a cryptically grooved chaperone that expands unfolded outer membrane proteins
Cui LabSelective capture and recovery of monoclonal antibodies by self-assembling supramolecular polymers of high affinity for protein binding
Culotta LabCopper-Only Superoxide Dismutase Enzymes and Iron Starvation Stress in Candida Fungal Pathogens
Fleming LabDomain interactions determine the conformational ensemble of the periplasmic chaperone SurA
Kavran LabBiophysical characterization fo SARAH domain-mediated multimerization of Hippo pathway complexes in Drosophila
Tovar LabComputationally guided tuning of amino acid configuration influences the chiroptical properties of supramolecular peptide-pi-peptide nanostructures


Barrick LabA second backbone: The contribution of a buried asparagine ladder to the global and local stability of a leucine-rich repeat protein
Tovar LabControlling supramolecular chirality in peptide-pi-peptide networks by variation of the alkyl spacer length
Meyers LabX-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1-deoxy-D-xylulose 5-phosphate synthase reaction coordinate
Barrick LabConsensus sequence design as a general strategy to create hyperstable, biologically active proteins
Ha LabExtreme mechanical diversity of human telomeric DNA revealed by fluorescence-force spectroscopy
Barrick and Ha LabsFunctional instability allows access to DNA in longer transcription Activator-Like effector (TALE) arrays
Barrick LabExtreme stability in de novo-designed repeats arrays is determined by unusually stable short-range interactions
Tovar LabTorsional impacts on quaterthiophene segments confined within peptidic nanostructures


Garcia-Moreno LabDielectric properties of a protein probed by reversal of a buried ion pair
Greenberg LabExpanded substrate scope of DNA polymerase theta and DNA polymerase beta: Lyase activity on the 5′-overhangs and clustered lesions
Elisseeff LabCyclodextrin Modulated Type I Collagen Self-Assembly to Engineer Biomimetic Cornea Implants
Greenberg LabMechanistic insight through irreversible inhibition:DNA polymerase theta uses a common active site for polymerase and lyase activities
Hilser LabAssessing allostery in intrinsically disordered protein with ensemble allosteric model
Hilser LabDynamic allostery can drive cold adaptation in enzymes
Lecomte LabLysine as a heme iron ligand: A property common to three truncated hemoglobins from Chlamydomonas reinhardtii
Lecomte LabReplacement of the distal histidine reveals a noncanonical heme binding site in a 2-on-2 hemoglobin
Meyers LabOxidative decarboxylation of pyruvate by 1-deoxy-D-xyulose 5-phosphate synthase, a central metabolic enzyme in bacteria


Barrick LabControl of transcriptional activity by design of charge patterning in the intrinsically disordered RAM region of the Notch receptor
Barrick LabCreating a homeodomain with high stability and DNA binding affinity by sequence averaging
Frueh LabMolecular cross-talk between nonribosomal peptide synthetase carrier proteins and unstructured linker regions 
Hilser LabStructural stability of the coiled-coil domain of tumor susceptibility
Tovar LabNonresonant and local field effects in peptidic nanostructures bearing oligo (p-phenylenevinylene) units
Tovar LabKinetically controlled coassembly of multichromophoric peptide hydrogelators and the impacts on energy transport


Barrick LabBroken TALEs: transcription activator-like effectors populate partly folded states
Tovar LabCross-linking approaches to tuning the mechanical properties of peptide π‑electrom hyrdogels


Barrick LabEffects of linker length and transient secondary structure elements in the intrinsically disordered Notch RAM region on Notch signaling
Barrick LabA naturally occurring repeat protein with high internal sequence identity defines a new class of TPR-like proteins
Bortvan LabA unique HMG-Box domain of mouse maelstrom binds structured RNA but not double stranded DNA
Tovar LabSequence-dependent mechanical, photophysical and electrical properties of pi-conjugated peptide hydrogelators
Ostermeier LabDesign of protein switches based on an ensemble model of allostery


Lecomte LabCharacterization of THB1, a Chlamydomonas reinhardtii truncated hemoglobin: linkage to nitrogen metabolism and identification of lysine as the distal heme ligand
Stivers LabGTP activator and dNTP substrates of HIV-1 restriction factor and SAMHD1 generate a long-lived activated state