Building Quaternary Structure in Heme Proteins

Funded by the National Science Foundation
CLP-2003950

Several unicellular photosynthetic organisms are known to produce one or more hemoglobins. The properties and function of these proteins remain mysteries that offer a window on heme chemistry and molecular evolution. The goal of the project is to study the formation of quaternary structure from monomeric microbial hemoglobins.  Because of the ancient origin of the hemoglobin superfamily, the properties of these hemoglobins under extreme conditions of pressure are also a focus of investigation.