Kaiser Lab – Home

The Kaiser lab is interested in understanding molecular processes in protein biogenesis. In particular, we are addressing the following questions:

How do multi-domain proteins, prevalent in all proteomes, fold into their functional structures?

What mechanisms do molecular chaperones employ to assist protein folding in the cytosol?

How are secreted and transmembrane proteins transported across biological membranes?

To address these questions, we are combining molecular biology and biochemistry approaches with single-molecule techniques. We complement these in vitro approaches with studies in live cells.

A brief “general interest” description of why protein folding is important can be found here, and a simplified description of optical tweezers here.

Please see the Research section for more information on our work.

We are actively recruiting graduate and undergraduate students. If you are interested in our work, please contact Christian directly.