150. Hughes, M. A.; McFadden, J. M.; Townsend, C. A. “New α-Methylene-γ-Butyrolactones with Antimycobacterial Properties,” Bioorg. Med. Chem. Lett. 2005, 15, 3857-3859.

149. Henry, K. M.; Townsend, C. A. “Ordering the Reductive and Cytochrome P450 Oxidative Steps in Demethylsterigmatocystin Formation Yields New Insights into Xanthone Biosynthesis,” J. Am. Chem. Soc. 2005, 127, 3724-3733.

148. Henry, K. M.; Townsend, C. A. “The Synthesis and Fate of o-Carboxybenzophenones in the Biosynthesis of Aflatoxin,” J. Am. Chem. Soc. 2005,127, 3300-3309.

147. McFadden, J. M.; Medghalchi, S. M.; Thupari, J. N.; Pinn, M, L.; Vadlamudi, A.; Miller, K. I.; Kuhajda, F. P.; Townsend, C. A. “Application of a Flexible Synthesis of (5R)-Thiolactomycin to Develop New Inhibitors of Type I Fatty Acid Synthase,” J. Med. Chem. 2005, 48, 946-961.

146. Kelly, W. L.; Townsend, C. A. “Mutational Analysis of nocK and nocL in the Nocardicin A Producer Nocardia uniformis,” J. Bacteriol. 2005,187, 739-746.

145. Gerratana, B.; Arnett, S. O.; Stapon, A.; Townsend, C. A. “Carboxymethylproline Synthase from Pectobacterium carotovora: A Multi-faceted Member of the Crotonase Superfamily,” Biochemistry 2004, 43, 15936-15945.

144. Kelly, W. L.; Townsend, C. A. “Mutational Analysis and Characterization of Nocardicin C-9′ Epimerase,” J. Biol. Chem. 2004, 279, 38220-38227.

143. Parrish, N. M.; Ko, C. G.; Hughes, M. A.; Townsend, C. A.; Dick, J. D. “Effect of n-Octanesulphonylacetamide (OSA) on ATP and Protein Expression in Mycobacterium bovis BCG,” J. Antimicrob. Chemother. 2004, 54, 722-729.

142. Chiou, C. H.; Lee, L. W.; Owens, S. A.; Whallon, J. H.; Klomparens, K. L.; Townsend, C. A.; Linz, J. E. “Distribution and Sub-Cellular Localization of the Aflatoxin Enzyme Versicolorin B Synthase in Time-Fractionated Colonies of Aspergillus parasiticus,” Arch. Microbiol. 2004,182, 67-79.

141. Gunsior, M.; Breazeale, S. D.; Lind, A. J.; Ravel, J.; Janc, J. W.; Townsend, C. A. “The Biosynthetic Gene Cluster for a Monocyclic β-Lactam Antibiotic, Nocardicin A,” Chem. & Biol. 2004, 11, 927-938.

140. Gunsior, M.; Ravel, J.; Challis, G. L.; Townsend, C. A. “Engineering p-Hydroxyphenylpyruvate Dioxygenase to a p-Hydroxymandelate Synthase and Evidence for the Proposed Benzene Oxide Intermediate in Homogentisate Formation,” Biochemistry 2004, 43, 663-674.

139. Stapon, A.; Li, R.; Townsend, C. A. “Synthesis of (3S,5R)-carbapenam-3-carboxylic acid and its role in carbapenem biosynthesis and the stereoinversion problem,” J. Am. Chem. Soc. 2003, 125, 15746-15747.

138. Zhou, W.; Simpson, P. J.; McFadden, J. M.; Townsend, C. A.; Medghalchi, S. M.; Vadlamudi, A.; Pinn, M. L.; Ronnett, G. V.; Kuhajda, F. P. “Fatty Acid Synthase Inhibition Triggers Apoptosis During S Phase in Human Cells,” Cancer Res. 2003, 63, 7330-7337.

137. Miller, M. T.; Gerratana, B.; Stapon, A.; Townsend, C. A.; Rosenzweig, A. C. “Crystal Structure of Carbapenem Synthetase (CarA),” J. Biol. Chem. 2003, 278, 40996-41002.

136. Gerratana, B.; Stapon, A.; Townsend, C. A. “Inhibition and Alternate Substrate Studies on the Mechanism of Carbapenam Synthetase from Erwinia carotovora,” Biochemistry 2003, 42, 7836-7847.

135. Stapon, A; Li, R.; Townsend, C. A. “Carbapenem Biosynthesis: Confirmation of Stereochemical Assignments and the Role of CarC in the Ring Stereoinversion Process from l-Proline,” J. Am. Chem. Soc. 2003, 125, 8486-8493.

134. McFadden, J. M.; Frehywot, G. L.; Townsend, C. A. “A Flexible Route to (5R)-Thiolactomycin, a Naturally-Occurring Inhibitor of Fatty Acid Synthesis,” Org. Lett. 2002, 4, 3859-3862.

133. Miller, M. T.; Bachmann, B. O.; Townsend, C. A.; Rosenzweig, A. C. “The Catalytic Cycle of β-Lactam Synthetase Observed by x-Ray Crystallographic Snapshots,” Proc. Natl. Acad. Sci. 2002, 99, 14752-14757.

132. Udwary, D. W.; Merski, M.; Townsend, C. A. “A Method for Prediction of the Locations of Linker Regions Within Large Multifunctional Proteins, and Application to a Type I Polyketide Synthase,” J. Mol. Biol. 2002, 323, 585-598.

131. Kim, E.-K.; Miller, I.; Landree, L. E.; Borisy-Rudin, F. F.; Brown, P.; Tihan, T.; Townsend, C. A.; Witters, L. A.; Moran, T. H.; Kuhajda, F. P.; Ronnett, G. V. “Expression of FAS Within Hypothalmic Neurons: A Model for Decreased Food Intake After C75 Treatment,” Am. J. Physiol. Endocrinol. Metab. 2002, 283, E867-E879.

130. Watanabe, C. M. H.; Townsend, C. A. “Initial Characterization of a Type I Fatty Acid Synthase and Polyketide Synthase Multienzyme Complex NorS in the Biosynthesis of Aflatoxin B₁,” Chem. & Biol. 2002, 9, 981-988.

129. Townsend, C. A. “New Reactions in Clavulanic Acid Biosynthesis,” Curr. Opin. Chem. Biol. 2002, 6, 583-589.

128. Kelly, W. L; Townsend, C. A. “Role of the Cytochrome P450 NocL in Nocardicin A Biosynthesis,” J. Am. Chem. Soc. 2002, 124, 8186-8187.

127. Udwary, D. W.; Casillas, L. K.; Townsend, C. A. “Synthesis of 11-Hydroxyl O-Methylsterigmatocystin and the Role of a Cytochrome P-450 in the Final Step of Aflatoxin Biosynthesis,” J. Am. Chem. Soc. 2002, 124, 5294-5303.

126. Miller, M. T.; Bachmann, B. O.; Townsend, C. A.; Rosenzweig, A. C. “Structure of β-Lactam Synthetase Reveals How To Synthesize Antibiotics Instead of Asparagine,” Nature Struct. Biol. 2001, 8, 684-689.

125. Hitchman, T. S.; Schmidt, E. W.; Trail, F.; Rarick, M. D.; Linz, J. E.; Townsend, C. A. “Hexanoate Synthase, a Specialized Type I Fatty Acid Synthase from Aflatoxin B₁ Biosynthesis,” Bioorg. Chem. 2001, 29, 293-307.

124. Zhou, J.; Kelly, W. L.; Bachmann, B. O.; Gunsior, M.; Townsend, C. A.; Solomon, E. I. “Spectroscopic Studies of Substrate Interactions with Clavaminate Synthase 2, a Multifunctional α-KG-Dependent Non-Heme Iron Enzyme: Correlation with Mechanisms and Reactivities,” J. Am. Chem. Soc. 2001, 123, 7388-7398.

123. Parrish, N. M.; Houston, T.; Jones, P. B.; Townsend, C. A.; Dick, J. D. “In Vitro Activity of a Novel Antimicrobial Compound, N-Octanesulfonylacetamide, and Its Effects on Lipid and Mycolic Acid Synthesis,” Antimicrob. Agents Chemother. 2001, 45, 1143-1150.