85. Chatterjee, M.; Mah, S. C.; Tullius, T. D.; Townsend, C. A. “Role of the Aryl Iodide in the Sequence-Selective Cleavage of DNA by Calicheamicin. Importance of Thermodynamic Binding vs. Kinetic Activation in the Cleavage Process,” J. Am. Chem. Soc. 1995, 117, 8074-8082.

84. Wu, T.-K.; Houston, T. A.; Busby, R. W.; McIlwaine, D. B.; Egan, L. A.; Townsend, C. A. “Identification, Cloning, Sequencing and Over-Expression of the Gene Encoding Proclavaminate Amidino Hydrolase and Characterization of Protein Function in Clavulanic Acid Biosynthesis,” J. Bacteriol. 1995, 177, 3714-3720.

83. Kuduvalli, P. N.; Townsend, C. A.; Tulllius, T. D. “Cleavage by Calicheamicin γ₁^I of DNA in a Nucleosome Formed on the 5S RNA Gene of Xenopus borealis,” Biochemistry 1995, 34, 3899-3906.

82. Janc, J. W.; Egan, L. A.; Townsend, C. A. “Purification and Characterization of Clavaminate Synthase from Streptomyces antibioticus: A Multifunctional Enzyme of Clavam Biosynthesis,” J. Biol. Chem. 1995, 270, 5399-5404.

81. Busby, R. W.; Chang, M. D.-T.; Busby, R. C.; Wimp, J.; Townsend, C. A. “Expression and Purification of Two Isozymes of Clavaminate Synthase and Initial Characterization of the Iron Binding Site. General Error Analysis in PCR Amplification,” J. Biol. Chem. 1995, 270, 4262-4269.

80. Chatterjee, M.; Cramer, K. D.; Townsend, C. A. “Kinetic vs. Thermodynamic Determinants in the Sequence Selectivity of DNA Cleavage by Calicheamicin,” J. Am. Chem. Soc. 1994, 116, 8819-8820.

79. Chatterjee, M.; Townsend, C. A. “Evidence for the Probable Final Steps in Aflatoxin Biosynthesis,” J. Org. Chem. 1994, 59, 4424-4429.

78. Mah, S. C.; Price, M. A.; Townsend, C. A.; Tullius, T. D. “Features of DNA Recognition for Oriented Binding and Cleavage by Calicheamicin,” A Symposium-in-Print, Tetrahedron 1994, 50, 1361-1378.

77. Mah, S. C.; Townsend, C. A.; Tullius, T. D. “Hydroxyl Radical Footprinting of Calicheamicin. Relationship of DNA Binding to Cleavage,” Biochemistry 1994, 33, 614-621.

76. De Voss, J. J.; Hangeland, J. J.; Townsend, C. A. “A General Approach to the Synthesis of Specifically Deuterium-Labeled Nucleosides,” J. Org. Chem. 1994, 59, 2715-2723.

75. Brobst, S. W.; Townsend, C. A. “The Potential Role of Fatty Acid Initiation in the Biosynthesis of the Fungal Aromatic Polyketide Aflatoxin B₁,” Ian Spenser commemorative issue of Can. J. Chem. 1994, 72, 200-207.

74. McIlwaine, D. B.; Townsend, C. A. “Evidence for Distinct Mechanisms of Monocyclic β-Lactam Biosynthesis,” J. Chem. Soc., Chem. Commun.1993, 1346-1347.

73. Janc, J. W.; Egan, L. A.; Townsend, C. A. “Emerging Evidence for a Shared Biosynthetic Pathway Among Clavulanic Acid and the Structurally Diverse Clavam Metabolites,” A Symposium-in-Print, Bioorg. Med. Chem. Letters 1993, 3, 2313-2316.

72. Iwata-Reuyl, D.; Basak, A.; Silverman, L. S.; Engle, C. A.; Townsend, C. A. “Synthesis and Reaction of Potential Mechanism-Based Inhibitors of Clavaminate Synthase,” Edward Leete memorial issue of J. Nat. Prod. 1993, 56, 1373-1396.

71. McGuire, S. M.; Townsend, C. A. “Demonstration of Baeyer-Villiger Oxidation and the Course of Cyclization in Bisfuran Ring Formation During Aflatoxin B₁ Biosynthesis,” Bioorg. & Med. Chem. Letters 1993, 3, 653-656.

70. Ellestad, G. A.; Zein, N.; Ding, W-D.; Townsend, C. A. “DNA Cleaving Properties of Calicheamicin γ₁^I.” In Enediyne Antibiotics as Antitumor Agents; Borders, D. B.; Doyle, T. W., Eds.; Marcel Dekker: New York, 1995, pp. 137-160.

69. Chatterjee, M.; Cramer, K. D.; Townsend, C. A. “The Kinetic Nature of Thiol Activation in DNA Cleavage by Calicheamicin,” J. Am. Chem. Soc.1993, 115, 3374-3375.

68. Townsend, C. A. “Oxidative Amino Acid Processing in β-Lactam Antibiotic Biosynthesis,” Trans. Biochem. Soc. 1993, 21, 208-213.

67. Hangeland, J. J.; De Voss, J. J.; Heath, J. A.; Townsend, C. A.; Ding, W.-d.; Ashcroft, J. S.; Ellestad, G. A. “Specific Abstraction of the 5’S- and 4′-Deoxyribosyl Hydrogen Atoms From DNA by Calicheamicin γ₁^I,” J. Am. Chem. Soc. 1992, 114, 9200-9202.

66. Marsh, E. N.; Chang, M. D.-T., Townsend, C. A. “Two Isoenzymes of Clavaminate Synthase Central to Clavulanic Acid Formation — Cloning and Sequencing of Both Genes from Streptomyces clavuligerus,” Biochemistry 1992, 31, 12648-12657.

65. Iwata-Reuyl, D.; Townsend, C. A. “Common Origin of Clavulanic Acid and Other Clavam Metabolites in Streptomyces,” J. Am. Chem. Soc. 1992, 114, 2762-2763.

64. Townsend, C. A.; McGuire, S. M.; Brobst, S. W.; Graybill, T. L.; Pal, K.; Barry III, C. E. “Examination of Tetrahydro- and Dihydrobisfuran Formation in Aflatoxin Biosynthesis from Whole Cells to Purified Enzymes.” In ACS Symposium Series, Secondary-Metabolite Biosynthesis and Metabolism; Petroski, R. J.; McCormick, S. P., Eds.; Plenum Press: New York, 1992; pp. 141-154.

63. Cramer, K. D.; Townsend, C. A. “Kinetics of Trisulfide Cleavage in Calicheamicin–Assessing the Role of the Ethylamino Group,” Tetrahedron Lett. 1991, 32, 4635-4638.

62. Townsend, C. A.; Basak, A. “Experiments and Speculations on the Role of Oxidative Cyclization Chemistry in Natural Product Biosynthesis,” A Symposium-in-Print, Tetrahedron 1991, 47, 2591-2602.

61. Salowe, S. P.; Krol, W. J.; Iwata-Reuyl, D.; Townsend, C. A. “Elucidation of the Order of Oxidations and Identification of an Intermediate in the Multi-Step Clavaminate Synthase Reaction,” Biochemistry 1991, 30, 2281-2292.

60. Krol, W. J.; Mao, S.-s.; Steele, D. L.; Townsend, C. A. “Stereochemical Correlation of Proclavaminic Acid and Syntheses of erythro- and threo-L-b-Hydroxyornithine from an Improved Vinylglycine Synthon,” J. Org. Chem. 1991, 56, 728-731.