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About Us:

Peptide nanomaterial design

We have developed several synthetic methods to incorporate electron-rich aromatic subunits into water-soluble peptide backbones. These materials spontaneous assemble into long fibers with optical and electronic responses similar to conventional silicon electronics and could potentially serve as new biocompatible organic electronics with uses in medical interventions and clean energy.

Relaxation distribution

Peptide sequence variation can be used to tune excited state photophysical outcomes (excitonic v.s. excimeric) and tailor electronic and mechanical properties of these assemblies. The molecular landscape is too vast for trial-and-improvement experiment, however, computational data-driven modeling can accelerate the search for promising peptide designs.

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Computationally, we have (i) developed an inexpensive molecular model of assembly to identify promising new chemistries for experimental testing, and (ii) used data-driven modeling to predict which peptide properties tend to lead to desired structures. Experimentally, we have used the insights from this data-driven modeling and have prepared peptide sequences expected to exhibit high extents of cofacial pi-stacking.  Ongoing efforts will examine the impacts of these interactions on electronic material properties.

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