Publications

Selected Publications:

  • Harms MJ, Schlessman JL, Sue GR, García-Moreno B. Arginine residues at internal positions in a protein are always charged. Proc Natl Acad Sci U S A. 2011 Nov 22; 108 (47) :18954-9.
  • Damjanovic A, Brooks BR, García-Moreno B. Conformational relaxation and water penetration coupled to ionization of internal groups in proteins. J Phys Chem A. 2011 Apr 28; 115 (16) :4042-53.
  • Isom DG, Castañeda CA, Cannon BR, García-Moreno B. Large shifts in pKa values of lysine residues buried inside a protein. Proc Natl Acad Sci U S A. 2011 Mar 29; 108 (13) :5260-5.
  • Schroer MA, Paulus M, Jeworrek C, Krywka C, Schmacke S, Zhai Y, Wieland DC, Sahle CJ, Chimenti M, Royer CA, Garcia-Moreno B, Tolan M, Winter R. High-pressure SAXS study of folded and unfolded ensembles of proteins. Biophys J. 2010 Nov 17; 99 (10) :3430-7.
  • Karp DA, Stahley MR, García-Moreno B. Conformational consequences of ionization of Lys, Asp, and Glu buried at position 66 in staphylococcal nuclease. Biochemistry. 2010 May 18; 49 (19) :4138-46.
  • Pey AL, Rodriguez-Larrea D, Gavira JA, Garcia-Moreno B, Sanchez-Ruiz JM. Modulation of buried ionizable groups in proteins with engineered surface charge. J Am Chem Soc. 2010 Feb 3; 132 (4) :1218-9.
  • Pais TM, Lamosa P, Garcia-Moreno B, Turner DL, Santos H. Relationship between protein stabilization and protein rigidification induced by mannosylglycerate. J Mol Biol. 2009 Nov 27; 394 (2) :237-50.
  • Garcia-Moreno B. Adaptations of proteins to cellular and subcellular pH. J Biol. 2009; 8 (11) :98.
  • Mitra L, Rouget JB, Garcia-Moreno B, Royer CA, Winter R. Towards a quantitative understanding of protein hydration and volumetric properties. Chemphyschem. 2008 Dec 22; 9 (18) :2715-21.
  • Isom DG, Cannon BR, Castañeda CA, Robinson A, García-Moreno B. High tolerance for ionizable residues in the hydrophobic interior of proteins. Proc Natl Acad Sci U S A. 2008 Nov 18; 105 (46) :17784-8.
  • Takayama Y, Castañeda CA, Chimenti M, García-Moreno B, Iwahara J. Direct evidence for deprotonation of a lysine side chain buried in the hydrophobic core of a protein. J Am Chem Soc. 2008 May 28; 130 (21) :6714-5.
  • Harms MJ, Schlessman JL, Chimenti MS, Sue GR, Damjanovic A, García-Moreno B. A buried lysine that titrates with a normal pKa: role of conformational flexibility at the protein-water interface as a determinant of pKa values. Protein Sci. 2008 May; 17 (5) :833-45.
  • Matousek WM, Ciani B, Fitch CA, Garcia-Moreno B, Kammerer RA, Alexandrescu AT. Electrostatic contributions to the stability of the GCN4 leucine zipper structure. J Mol Biol. 2007 Nov 16; 374 (1) :206-19.
  • Brun L, Isom DG, Velu P, García-Moreno B, Royer CA. Hydration of the folding transition state ensemble of a protein. Biochemistry. 2006 Mar 21; 45 (11) :3473-80.
  • Damjanovic A, García-Moreno B, Lattman EE, García AE. Molecular dynamics study of water penetration in staphylococcal nuclease. Proteins. 2005 Aug 15; 60 (3) :433-49.
  • García-Moreno B, Dwyer JJ, Gittis AG, Lattman EE, Spencer DS, Stites WE. Experimental measurement of the effective dielectric in the hydrophobic core of a protein. Biophys Chem. 1997 Feb 28; 64 (1-3) :211-24.
  • Meeker AK, Garcia-Moreno B, Shortle D. Contributions of the ionizable amino acids to the stability of staphylococcal nuclease. Biochemistry. 1996 May 21; 35 (20) :6443-9.